Derek Thompson has a short interview with Steve Blank about Facebook’s IPO and what it means for Silicon Valley:

Facebook’s success has the unintended consequence of leading to the demise of Silicon Valley as a place where investors take big risks on advanced science and tech that helps the world. The golden age of Silicon valley is over and we’re dancing on its grave. On the other hand, Facebook is a great company. I feel bittersweet.

Why is that?

Silicon Valley historically would invest in science, and technology, and, you know, actual silicon. If you were a good VC you could make $100 million. Now there’s a new pattern created by two big ideas. First, for the first time ever, you have computer devices, mobile and tablet especially, in the hands of billions of people. Second is that we are moving all the social needs that we used to do face-to-face, and we’re doing them on a computer.

And this trend has just begun.

In other words, opportunities to make lots of money quickly on bubblicious things tend to draw attention away from hard things that offer more enduring value. Makes perfect sense. Blank also makes this interesting observation:

I see my students trying to commercialize really hard stuff. But the VCs are only going to be interested in chasing the billions on their smart phones. Thank God we have small business research grants from the federal government, otherwise the Chinese would just grab them….

The four most interesting projects in the last five years are Tesla, SpaceX, Google Driving, and Google Goggles. That is one individual, Elon Musk, and one company, Google, doing all four things that are truly Silicon Valley-class disruptive…. Thank God for federal government grants, and the NIH, and Musk, and Google.